Variables in unit LC50 mg/L, but the user can change the unit to LC50, Thresholds and the measure endpoint most sensitive to the substance.Īs a default the computed probability distributions are show for the This figure shows the most probable toxicity interval of the substanceĪs well as the probability of the LC50 being below two different fixed The top part of the page shows the main conclusions from the analysis as shown in the figure below.
#Hugin bayesian pdf#
The information on the page also goes into the PDF report that can be There are different pieces of information that are relevant toĬonsider and a number of opportunities to get additional details. This page is where the results of the analysis are shown to the Outside of the applicability domain of the underlying model. The warning conclusion indicates if the substance is flagged as The next figure shows the warning conclusion based on the warning factors. The next figure shows the data on toxicity to fish gill cytoxicity where one value is available. The next figure shows the data on toxicity to fish embryo where five values are available. It is clear that two values are available for algae and two values are available for daphnids. The next figure shows the data on toxicity to algae and daphids. The next figure shows the data on QSAR-predicted toxicity to fish. The below data shows the data to determine the substance group based on the physical and chemical properties of the substance. It is mainly to check that the values have been correctly entered into the system. Users are not supposed to enter or change values on the pages. Transformation to the scale mol/L (log10). Toxicity values (EC50 and LC50) the values are shown after The figures below show the pages with entered data as well as values derivedĭirectly from the entered data (e.g., the substance group). Transformation of the data can be determined by navigating to the Show Once the data is uploaded, the validity of the upload and the Once the Reset button is pressed, the data is removed from the model.
Notice: The data is sent to the server for calculations, but the data is not stored. To make it easy for the user to try the system on already existingĭata, we have included four buttons where each button represents a Please note again that the upload process may be quite longĭepending on the speed of your internet connection. Once the data upload process is complete the substance name Carbamazepine isĭisplayed in the input field for the substance name. Observations on Embryo, two values on Algae and two values on Daphnia. Please be patientĪs can be seen from the above figure, the data contains five 5 May take a LONG time in the current implementation. Is pressed the data in the input file is uploaded to the server. Once the data is formattedĬorrectly, the Load button should be pressed. It may be necessary to navigate to the bottom of the dialog to Is selected the formatting of the data changes and will appear as Is clear that the separator symbol is ' '. Not be loaded correctly and the system will fail. Select the separator symbol used in the file otherwise the data will
Here it is very important to follow the instructions to XLSX file the dialog showing the content of the file will look The File is uploaded, a new dialog showing the content of the file will Use the Fileĭialog to lcoate and select the input file that you want to use. Once the button is pressed a Fileĭialog where the input file can be selected appears. To upload a data file (using the XLSX template file), you need to This information is used in the PDF-report that can be generatedīased on the results of the calculation. Used to separate the integer part of the value from the fractionalĪfter uploading the data, the user can enter author name and author organisation using the input fields shown below: Radix point or radix character) must be dot. It is important that the data follows the format used in the The input dialog or (preferred option) to organize the data using the It is assumed that the user has the data for the analysis availableĪnd is able to enter this data into the system either manually thorugh The analysis of a substance using SWiFT platform has four main steps: The purpose is not to explain the underlying theory The documentation is solely to demonstrate and explain how the user Toxicity from multiple lines of evidence. SWiFT weight-of-evidence platform can be used to predict fish acute The purpose of this user guide is to explain to the user how the Interactive guidance document on the use of the Bayesian network and its web-based interface ( Work in Progress) Technical User Guide
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